PERSPECTIVES IN PHARMACOLOGY Therapeutic Potential of Phosphatidylinositol 3-Kinase Inhibitors in Inflammatory Respiratory Disease
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The Endogenous Cannabinoid Anandamide Produces -9Tetrahydrocannabinol-Like Discriminative and Neurochemical Effects That Are Enhanced by Inhibition of Fatty Acid Amide Hydrolase but Not by Inhibition of Anandamide Transport Marcello Solinas, Gianluigi Tanda, Zuzana Justinova, Carrie E. Wertheim, Sevil Yasar, Daniele Piomelli, Subramanian K. Vadivel, Alexandros Makriyannis, and Steven R. Goldberg 370
منابع مشابه
Therapeutic potential of phosphatidylinositol 3-kinase inhibitors in inflammatory respiratory disease.
The phosphoinositide 3-kinase(s) (PI3K) are a family of proteins that catalyze the phosphorylation of the 3-OH position of phosphoinositides and generate lipids that control a wide variety of intracellular signaling pathways. They are classified into three families according to their structure and substrate specificity and are thought to have distinct biological roles. Recent studies suggested ...
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تاریخ انتشار 2007